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Chronic kidney disease (CKD) is largely preventable and treatable, but its burden continues to grow, particularly in low- and middle-income nations.1 The global kidney health community has long advocated implementing CKD detection and treatment programs, but robust health economic evidence to (…) (Kidney International Reports (2024))
00:00Immunoadsorption and plasma exchange are comparable in ANCA or anti-GBM removal kinetics. -
Marion SALLEE, Noémie RESSEGUIER, Thomas CREPIN, Daniel BERTIN, Dominique BERTRAND, Mickaël BOBOT, Thierry KRUMMEL, Nicolas MAILLARD, Julie MOUSSI-FRANCES, Marion PELLETIER, Pascale POULLIN, Cédric RAFAT, Thomas ROBERT, Benjamin TERRIER, Lionel ROSTAING, Stanislas FAGUER, Noémie JOURDE-CHICHE
Kidney Int Reports
Apheresis allows the fast removal of auto-antibodies in anti-glomerular basement membrane (GBM) disease, and in severe ANCA-associated vasculitis. The CINEVAS study tested whether immunoadsorption (IA) allowed a faster removal of ANCA and/or anti-GBM antibodies than plasma exchanges (PEx). (Kidney International Reports (2024))
00:00Exploring Apixaban Pharmacokinetics, Pharmacodynamics and Safety in Hemodiafiltration Patients. -
Aurema Otero, Elena Rosselló-Palmer, Sergi Codina, Nuria Lloberas, Yurema Martínez, Naiara Santos, Judith Peñafiel, Raúl Rigo-Bonnin, Anna Vidal, Joan Peris, Sebastià Videla, Miguel Hueso
Kidney Int Reports
Direct oral anticoagulants (DOACs) have replaced vitamin K antagonists in the general population with non-valvular atrial fibrillation (NVAF) due to their predictable anticoagulation profile, similar efficacy, and superior safety. However, their benefits remain unclear in dialysis patients since (…) (Kidney International Reports (2024))
00:00A Randomized Controlled Trial Comparing Automated Peritoneal Dialysis and Hemodialysis for Urgent-Start Dialysis in End-Stage Renal Disease -
Haijiao Jin, Wei Fang, Ling Wang, Xiujuan Zang, Yueyi Deng, Guoqing Wu, Ying Li, Xiaonong Chen, Niansong Wang, Gengru Jiang, Zhiyong Guo, Xiaoxia Wang, Yinghui Qi, Shifan Lv, Zhaohui Ni
Kidney Int Reports
Peritoneal dialysis (PD) shows promise for urgent-start dialysis in end-stage renal disease (ESRD), with automated PD (APD) having advantages. However, there is limited multi-center randomized controlled trial (RCT) evidence comparing APD versus temporary hemodialysis (HD) for this indication in (…) (Kidney International Reports (2024))
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Individuals of recent West African ancestry develop focal segmental glomerulosclerosis (FSGS) and hypertension-attributed end stage kidney disease (HTN-ESKD) at 4 times the rate of White Americans. Two protein-coding variants of the Apolipoprotein L1 (APOL1) gene, G1 and G2, explain 50% to 70% (…) (Kidney International Reports (2024))